Date Published: July 01, 2011
Publisher: International Union of Crystallography
Author(s): Dan-Li Tian, Gang Luo, Hong Chen, Xiao-Wei Tang, Yong-Feng Liu.
In title compound, C16H17FN2O2, the cyclohexane ring adopts a chair conformation.. The crystal packing is stabilized by weak π–π stacking interactions [centroid–centroid distance = 3.503 (5) Å] and intermolecular C—H⋯O, N—H⋯O and N—H⋯F hydrogen-bond interactions.
For the biological activity of the title compound and its derivatives, see: Souli et al. (2008 ▶); Chai et al. (2006 ▶); Radwan et al. (2007 ▶); Karthikeyan et al. (2009 ▶). For the preparation, see: Bacher et al. (2001 ▶). For bond-length and angle data for similar structures, see: Liu et al. (2011 ▶); Sonar et al. (2006 ▶).