Research Article: N-Cyclo­hexyl-2-(5-fluoro-1H-indol-3-yl)-2-oxoacetamide

Date Published: July 01, 2011

Publisher: International Union of Crystallography

Author(s): Dan-Li Tian, Gang Luo, Hong Chen, Xiao-Wei Tang, Yong-Feng Liu.

http://doi.org/10.1107/S1600536811024299

Abstract

In title compound, C16H17FN2O2, the cyclo­hexane ring adopts a chair conformation.. The crystal packing is stabilized by weak π–π stacking inter­actions [centroid–centroid distance = 3.503 (5) Å] and inter­molecular C—H⋯O, N—H⋯O and N—H⋯F hydrogen-bond inter­actions.

Partial Text

For the biological activity of the title compound and its deriv­atives, see: Souli et al. (2008 ▶); Chai et al. (2006 ▶); Radwan et al. (2007 ▶); Karthikeyan et al. (2009 ▶). For the preparation, see: Bacher et al. (2001 ▶). For bond-length and angle data for similar structures, see: Liu et al. (2011 ▶); Sonar et al. (2006 ▶).

Source:

http://doi.org/10.1107/S1600536811024299