Research Article: N-Cyclo­hexyl-N′-(4-nitro­benzo­yl)thio­urea

Date Published: May 01, 2010

Publisher: International Union of Crystallography

Author(s): Sohail Saeed, Naghmana Rashid, Wing-Tak Wong.


In the title compound, C14H17N3O3S, the nitro group is twisted slightly by 2.6 (3)° from the benzene ring plane and the thio­ureido group makes a dihedral angle of 52.06 (4)° with the benzene ring. The cyclo­hexyl ring displays a chair conformation. An intra­molecular N—H⋯O inter­action is present. In the crystal, inter­molecular N—H⋯S hydrogen bonds link the mol­ecules into centrosymmetric dimers. π–π inter­actions between inversion-related benzene rings (centroid–centroid distance = 4.044 Å) and C—H⋯π inter­actions (H⋯centroid distance = 3.116 Å) between one methyl­ene cyclo­hexyl H atom and the benzene ring are also present.

Partial Text

For general background to the chemistry and biological activity of thio­urea derivatives and their use as organic synthons or as complexing agents, see: Glasser & Doughty (1964 ▶); Jain & Rao (2003 ▶); Zeng et al. (2003 ▶); Xu et al. (2004 ▶); Zheng et al. (2004 ▶); D’hooghe et al. (2005 ▶); Saeed et al. (2008 ▶, 2009 ▶, 2010 ▶).




0 0 vote
Article Rating
Notify of
Inline Feedbacks
View all comments