Research Article: Research Ethics and Reporting Standards at PLoS Neglected Tropical Diseases

Date Published: October 31, 2007

Publisher: Public Library of Science

Author(s): Gavin Yamey

Abstract: None

Partial Text: PLoS Neglected Tropical Diseases has been open to submissions since February 2007, and we have been impressed by the number, quality, and range of the research articles we have received to date—from laboratory studies and assessments of new diagnostic tests to observational epidemiology, clinical trials, and qualitative research. But we have also noted that some authors have omitted crucial information about the ethical conduct of their study, or have been unaware of international guidance on how to report specific types of research. We would therefore like to remind authors of our reporting requirements (more detailed guidance is available at

Patients with neglected tropical diseases are among the most economically and socially disadvantaged people on the planet. So when it comes to conducting clinical research among this vulnerable population, investigators must take particular precautions to protect the welfare of research participants.

One of the most important advances in medical research reporting has been the development of international standards for reporting specific study types. PLoS has adopted these standards for all of its journals. The best known is the CONSORT (Consolidated Standards of Reporting Trials) statement. Authors should supply a completed CONSORT checklist (available from the CONSORT Web site at and ensure that they include a flow diagram to illustrate participant flow through the trial. In addition, we strongly encourage authors to write their paper using a template that adopts the CONSORT section headings, and we have prepared such a template for you to use (available at



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