Date Published: September 4, 2013
Publisher: BioMed Central
Author(s): Nicolas Bertholet, Joseph Studer, John A Cunningham, Jean-Bernard Daeppen, Gerhard Gmel, Bernard Burnand.
How much a randomized controlled trial (RCT) sample is representative/differs from its declared source population is a challenging question, with major implications with regard to generalizibility of results. The question is crucial for freely available web-based interventions tested in RCTs.