Research Article: Significant Reduction of Antibiotic Use in the Community after a Nationwide Campaign in France, 2002–2007

Date Published: June 2, 2009

Publisher: Public Library of Science

Author(s): Elifsu Sabuncu, Julie David, Claire Bernède-Bauduin, Sophie Pépin, Michel Leroy, Pierre-Yves Boëlle, Laurence Watier, Didier Guillemot, Keith P. Klugman

Abstract: Didier Guillemot and colleagues describe the evaluation of a nationwide programme in France aimed at decreasing unnecessary outpatient prescriptions for antibiotics. The campaign was successful, particularly in reducing prescriptions for children.

Partial Text: The emergence and the dissemination of drug-resistant bacterial strains make treatment decisions challenging and may be associated with treatment failures. This phenomenon has become a major public health issue.

Between 2002 and 2007, we observed an overall 26.5% reduction (adjusted for FLS fluctuations) of winter antibiotic prescriptions in France; the reduction was consistent across all age groups and all 22 regions, as well as across the most frequently used therapeutic classes. The initial objective of the “Keep Antibiotics Working” program to reduce antibiotic use in the community by 25% was reached in 5 years.