Date Published: June 01, 2010
Publisher: International Union of Crystallography
Author(s): Yan Meng, Yanqing Miao.
The title compound, C10H9NO3, was synthesized by the condensation reaction of isatin (systematic name 1H-indole-2,3-dione) with glycol in presence of p-toluenesulfonic acid. The indol-2-one ring system is essentially planar [N—C—C—C torsion angle = 3.1 (2)°], and the 1,3-dioxolane ring is slightly distorted. The crystal structure exhibits intermolecular N—H⋯O hydrogen bonds.
For the synthesis of the title compound, see: Santos et al. (2008 ▶). For the bioactivity of the title compound, see: Demosthenes et al. (1998 ▶); Rajopadhye & Popp (1988 ▶).