Date Published: August 01, 2012
Publisher: International Union of Crystallography
Author(s): Konstantin V. Kudryavtsev, Sergey Z. Vatsadze, Vera S. Semashko, Andrei V. Churakov.
In the title compound, C16H23ClN2O, both six-membered rings adopt chair conformations, thus allowing the formation of an intramolecular N—H⋯N hydrogen bond. In the crystal, adjacent molecules are combined into chains running along the ac diagonal via O—H⋯N hydrogen bonds.
For general background to chemistry affording syn-3,7-diazabicyclo[3.3.1]nonan-9-ols, see: Vatsadze et al. (2006 ▶). 3,5,6,7-Tetrasubstituted 3,6-diazabicyclo[3.2.1]octanes, their biological activity as enzyme inhibitors and their X-ray structures have been reported by: Kudryavtsev (2010 ▶); Kudryavtsev & Churakov (2012 ▶).