Research Article: syn-3-(4-Chloro­benz­yl)-1,5-dimethyl-3,7-diaza­bicyclo­[3.3.1]nonan-9-ol

Date Published: August 01, 2012

Publisher: International Union of Crystallography

Author(s): Konstantin V. Kudryavtsev, Sergey Z. Vatsadze, Vera S. Semashko, Andrei V. Churakov.

http://doi.org/10.1107/S1600536812030310

Abstract

In the title compound, C16H23ClN2O, both six-membered rings adopt chair conformations, thus allowing the formation of an intra­molecular N—H⋯N hydrogen bond. In the crystal, adjacent mol­ecules are combined into chains running along the ac diagonal via O—H⋯N hydrogen bonds.

Partial Text

For general background to chemistry affording syn-3,7-diaza­bicyclo­[3.3.1]nonan-9-ols, see: Vatsadze et al. (2006 ▶). 3,5,6,7-Tetra­substituted 3,6-diaza­bicyclo­[3.2.1]octa­nes, their biological activity as enzyme inhibitors and their X-ray structures have been reported by: Kudryavtsev (2010 ▶); Kudryavtsev & Churakov (2012 ▶).

 

Source:

http://doi.org/10.1107/S1600536812030310

 

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