Research Article: tert-Butyl 4-isopropyl-2-oxo-6-phenyl-3,4-dihydro-2H-pyran-3-carboxyl­ate

Date Published: May 01, 2010

Publisher: International Union of Crystallography

Author(s): Wei Chen, Miao Yu, Si Li, Ning Jiao.

http://doi.org/10.1107/S160053681001367X

Abstract

In the title compound, C19H24O4, the six-membered lactone ring adopts an envelope conformation with the tert-butoxy­carbonyl and isopropyl substituents in axial positions, and the phenyl group in an equatorial position. In the crystal structure, weak inter­molecular C—H⋯O hydrogen bonds link the mol­ecules into centrosymmetric dimers.

Partial Text

For the applications and synthesis of endocyclic enol lactones, see: Davies & Jin (2004 ▶); Evans et al. (2005 ▶); Krafft & Katzenellenbogen (1981 ▶); Li et al. (2007 ▶); Zeni et al. (2004 ▶); Zhao et al. (1997 ▶); Jimenez-Tenorio et al. (2001 ▶). For the synthesis, see: Li et al. (2009 ▶).

Source:

http://doi.org/10.1107/S160053681001367X