Research Article: Tetra­methyl N,N′-(2,2,3,3,4,4-hexa­fluoro-1,5-dioxopentane-1,5-di­yl)bis­(phospho­ramidate)

Date Published: April 01, 2012

Publisher: International Union of Crystallography

Author(s): Victor A. Trush, Kateryna E. Gubina, Yaroslav O. Gumeniuk, Tetyana Yu. Sliva, Irina S. Konovalova.


The mol­ecule of the title compound, C9H14F6N2O8P2, lies on a twofold rotation axis that passes through the middle C atom of the three-atom fluoro­methyl­ene unit. The carbonyl and phosphoryl groups are in an antiperiplanar conformation. In the crystal, N—H⋯O=P hydrogen bonds link the mol­ecules into polymeric chains parallel to the c axis.

Partial Text

For background to the chemistry of phospho­rus–organic compounds, see: Ly & Woollins (1998 ▶). For the biological and pharmacological properties of carbacyl­amido­phosphate der­iv­atives, see: Adams et al. (2002 ▶). For details of the synthesis and properties of phospho­ramide derivatives, see: Kirsanov & Levchenko (1957 ▶); For structural analogues of phospho­rylated carbacyl­amides and their properties, see: Trush et al. (2005 ▶); Gubina et al. (2000 ▶). For the synthesis and properties of fluorinated compounds, see: Leontieva et al. (2002 ▶).