Date Published: April 8, 2012
Publisher: Hindawi Publishing Corporation
Author(s): D. Kok, R. D. Donk, F. H. Wapstra, A. G. Veldhuizen.
Study Design/Objective. A single-centre, prospective, non-comparative study of 25 patients to evaluate the performance and safety of the Memory Metal Minimal Access Cage (MAC) in Lumbar Interbody Fusion. Summary of Background Data. Interbody fusion cages in general are designed to withstand high axial loads and in the meantime to allow ingrowth of new bone for bony fusion. In many cages the contact area with the endplate is rather large leaving a relatively small contact area for the bone graft with the adjacent host bone. MAC is constructed from the memory metal Nitinol and builds on the concept of sufficient axial support in combination with a large contact area of the graft facilitating bony ingrowth and ease in minimal access implantation due to its high deformability. Methods. Twenty five subjects with a primary diagnosis of disabling back and radicular leg pain from a single level degenerative lumbar disc underwent an interbody fusion using MAC and pedicle screws. Clinical performance was evaluated prospectively over 2 years using the Oswestry Disability Index (ODI), Short Form 36 questionnaire (SF-36) and pain visual analogue scale (VAS) scores. The interbody fusion status was assessed using conventional radiographs and CT scan. Safety of the device was studied by registration of intra- and post-operative adverse effects. Results. Clinical performance improved significantly (P < .0018), CT scan confirmed solid fusion in all 25 patients at two year follow-up. In two patients migration of the cage occurred, which was resolved uneventfully by placing a larger size at the subsequent revision. Conclusions. We conclude that the Memory Metal Minimal Access Cage (MAC) resulted in 100% solid fusions in 2 years and proved to be safe, although two patients required revision surgery in order to achieve solid fusion.
Chronic low back pain is an insidious problem. Individuals suffer from prolonged discomfort, anxiety, and disability. Low back pain has been shown as the leading cause of man-hours lost to disease or injury. Degeneration of the intervertebral disc is the most common cause of low back pain .
In this study, a prospective followup on clinical and radiographic parameters was performed in patients with a single level spondylodesis using a new interbody cage design.
The Memory Metal Minimal Access Cage performed very well radiographically and clinically. There was a 100 percent interbody fusion at 2 years on CT, no subsidence and significant improvement of clinically important outcomes, although two patients required revision surgery in order to achieve solid fusion.