Research Article: (Z)-3-(1-Benzofuran-2-yl)-2-(3,4,5-tri­meth­oxy­phen­yl)acrylonitrile

Date Published: March 01, 2012

Publisher: International Union of Crystallography

Author(s): Narsimha Reddy Penthala, Sean Parkin, Peter A. Crooks.


In the title compound, C20H17NO4, the double bond of the acrylonitrile group separating the 1-benzofuran moiety from the 3,4,5-trimeth­oxy­phenyl ring has Z geometry. The 1-benzofuran groups are π–π stacked with inversion-related counterparts such that the furan ring centroid–centroid distance is 3.804 (5) Å. The dihedral angle between the planes of the trimeth­oxy­phenyl ring and the acrylonitrile group is 24.2 (2)°.

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For the biological activity, see: Naruto et al. (1983 ▶); Parmar et al. (1988 ▶); Shiba (1996 ▶); Sanna et al. (1999 ▶, 2000 ▶); Ohsumi et al. (1998 ▶); Saczewski et al. (2004 ▶). For similar structures, see: Choi et al. (2007 ▶); Seo et al. (2009 ▶); Sonar et al. (2007 ▶).