suprachiasmatic nucleus | definition

area of the hypothalamus in which the body’s biological clock is located


Source:

Spielman, R. M., Jenkins, W. J., & Lovett, M. D. (2020). Psychology 2e. Houston, Texas: OpenStax. Access for free at https://openstax.org/details/books/psychology-2e

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Research Article: Antibodies for Assessing Circadian Clock Proteins in the Rodent Suprachiasmatic Nucleus

Date Published: April 27, 2012 Publisher: Public Library of Science Author(s): Joseph LeSauter, Christopher M. Lambert, Margaret R. Robotham, Zina Model, Rae Silver, David R. Weaver, Shin Yamazaki. http://doi.org/10.1371/journal.pone.0035938 Abstract Research on the mechanisms underlying circadian rhythmicity and the response of brain and body clocks to environmental and physiological challenges requires assessing levels of circadian clock … Continue reading

Research Article: The Role of the Suprachiasmatic Nucleus in Cardiac Autonomic Control during Sleep

Date Published: March 24, 2016 Publisher: Public Library of Science Author(s): S. D. Joustra, R. H. Reijntjes, A. M. Pereira, G. J. Lammers, N. R. Biermasz, R. D. Thijs, Raffaele Ferri. http://doi.org/10.1371/journal.pone.0152390 Abstract: The suprachiasmatic nucleus (SCN) may play an important role in central autonomic control, since its projections connect to (para)sympathetic relay stations in … Continue reading

Research Article: Intrinsic Regulation of Spatiotemporal Organization within the Suprachiasmatic Nucleus

Date Published: January 7, 2011 Publisher: Public Library of Science Author(s): Jennifer A. Evans, Tanya L. Leise, Oscar Castanon-Cervantes, Alec J. Davidson, Shin Yamazaki. http://doi.org/10.1371/journal.pone.0015869 Abstract: The mammalian pacemaker in the suprachiasmatic nucleus (SCN) contains a population of neural oscillators capable of sustaining cell-autonomous rhythms in gene expression and electrical firing. A critical question for understanding … Continue reading

Research Article: Synchronization-Induced Rhythmicity of Circadian Oscillators in the Suprachiasmatic Nucleus

Date Published: April 13, 2007 Publisher: Public Library of Science Author(s): Samuel Bernard, Didier Gonze, Branka Čajavec, Hanspeter Herzel, Achim Kramer, Karl J Friston Abstract: The suprachiasmatic nuclei (SCN) host a robust, self-sustained circadian pacemaker that coordinates physiological rhythms with the daily changes in the environment. Neuronal clocks within the SCN form a heterogeneous network … Continue reading

Research Article: Phase Differences in Expression of Circadian Clock Genes in the Central Nucleus of the Amygdala, Dentate Gyrus, and Suprachiasmatic Nucleus in the Rat

Date Published: July 28, 2014 Publisher: Public Library of Science Author(s): Valerie L. Harbour, Yuval Weigl, Barry Robinson, Shimon Amir, Paul A. Bartell. http://doi.org/10.1371/journal.pone.0103309 Abstract: We performed a high temporal resolution analysis of the transcript level of two core clock genes, Period2 (Per2) and Bmal1, and a clock output gene, Dbp, in the suprachiasmatic nucleus … Continue reading

Research Article: Photic Desynchronization of Two Subgroups of Circadian Oscillators in a Network Model of the Suprachiasmatic Nucleus with Dispersed Coupling Strengths

Date Published: May 16, 2012 Publisher: Public Library of Science Author(s): Changgui Gu, Zonghua Liu, William J. Schwartz, Premananda Indic, Shin Yamazaki. http://doi.org/10.1371/journal.pone.0036900 Abstract: The suprachiasmatic nucleus (SCN) is the master circadian clock in mammals and is composed of thousands of neuronal oscillators expressing different intrinsic periods. These oscillators form a coupled network with a free-running … Continue reading

Research Article: Intracellular Calcium Spikes in Rat Suprachiasmatic Nucleus Neurons Induced by BAPTA-Based Calcium Dyes

Date Published: March 10, 2010 Publisher: Public Library of Science Author(s): Jin Hee Hong, Cheol Hong Min, Byeongha Jeong, Tomoyoshi Kojiya, Eri Morioka, Takeharu Nagai, Masayuki Ikeda, Kyoung J. Lee, Shin Yamazaki. http://doi.org/10.1371/journal.pone.0009634 Abstract: Circadian rhythms in spontaneous action potential (AP) firing frequencies and in cytosolic free calcium concentrations have been reported for mammalian circadian pacemaker … Continue reading

Research Article: The day/night difference in the circadian clock’s response to acute lipopolysaccharide and the rhythmic Stat3 expression in the rat suprachiasmatic nucleus

Date Published: September 28, 2018 Publisher: Public Library of Science Author(s): Simona Moravcová, Dominika Pačesová, Barbora Melkes, Hana Kyclerová, Veronika Spišská, Jiří Novotný, Zdenka Bendová, Henrik Oster. http://doi.org/10.1371/journal.pone.0199405 Abstract The circadian clock in the suprachiasmatic nucleus (SCN) regulates daily rhythms in physiology and behaviour and is an important part of the mammalian homeostatic system. Previously, … Continue reading

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